Adhesions ring: a structural comparison between podosomes and the immune synapse.
نویسندگان
چکیده
Podosomes and the immune synapse are integrin-mediated adhesive structures that share a common ring-like morphology. Both podosomes and immune synapses have a central core surrounded by a peripheral ring containing talin, vinculin and paxillin. Recent progress suggests significant parallels between the regulatory mechanisms that contribute to the formation of these adhesive structures. In this review, we compare the structures, functions and regulation of podosomes and the immune synapse.
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عنوان ژورنال:
- European journal of cell biology
دوره 87 8-9 شماره
صفحات -
تاریخ انتشار 2008